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Answer: Surprising behavior for DEXseq dispersion estimate plot?
by
Snow
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0
Interesting adaptation of DEXseq, Elijah! Seeing those dispersion estimates makes me think about optimizing slopes, just like in [Snow Ride…
Answer: library org.Hs.eg.db failing to install
by
James W. MacDonald
68k
It should just install.
```
> library(BiocManager)
Bioconductor version 3.20
(BiocManager 1.30.25), R 4.4.1
(2024-06-14 ucrt)
W…
Comment: Surprising behavior for DEXseq dispersion estimate plot?
by
Elijah
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0
Thank you so much for your quick reply!
I was worried if some underlying technical artifact or unusual behavior would be causing the patter…
Answer: Surprising behavior for DEXseq dispersion estimate plot?
by
Michael Love
43k
The red points are just slowly moving toward -Inf. They tend to have variance < mean (if it were a simple design and you could just look at…
Answer: DESeq use in lipidomic analysis
by
Michael Love
43k
I would go for limma rather than a NB-based method. See the papers on limma for metabolomics / proteomics.
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